FeCl3-promoted alkylation of indoles by enamides.
نویسندگان
چکیده
An efficient iron-promoted alkylation of indoles with enamides has been accomplished under mild reaction conditions. The reaction proceeded with remarkable regioselectivity leading exclusively to substitution by indoles at α-position of enamides.
منابع مشابه
Direct alkylation of indoles and amines by tert-enamides: facile access to pharmaceutically active 2-oxo-1-pyrrolidine analogues.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 9 1 شماره
صفحات -
تاریخ انتشار 2011